MELFALAN OTOLOG KÖK HÜCRE NAKLİ HAZIRLIK PROTOKOLÜ

Kaynaklar:

1-Moreau, P., T. Facon, M. Attal, et al. 2002. "Comparison of 200 mg/m(2) melphalan and 8 Gy total body irradiation plus 140 mg/m(2) melphalan as conditioning regimens for peripheral blood stem cell transplantation in patients with newly diagnosed multiple myeloma: final analysis of the Intergroupe Francophone du Myelome 9502 randomized trial." Blood. 99(3):731-735.

2-Child, J. A., G. J. Morgan, F. E. Davies, et al. 2003. "High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma." N.Engl.J.Med. 348(19):1875-1883.

3-Bensinger, W. I., P. S. Becker, T. A. Gooley, et al. 2016. "A randomized study of melphalan 200 mg/m(2) vs 280 mg/m(2) as a preparative regimen for patients with multiple myeloma undergoing auto-SCT." Bone Marrow Transplant 51(1):67-71.

4-Blade J, Rosignol L, Sureda A et al. 2005."PETHEMA. High dose therapy intensification compared with continuous standard chemotherapy in multiple myeloma patients responding to the initial chemotherapy: Long term results from a prospective randomised trial from the Spanish co-operative group PETHEMA" Blood 106:3755-9

5-Fernand JP, Katsahian S, Divine M et al. 2005."High dose therapy and autologous blood stem cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65, Long term results of a randomised trial from the MAG"J Clin Oncol. 23:9227-33.

6-Levy V, Katsehian S, Fernand JP et al. 2005 "A meta-analysis of data from 575 patients with multiple myeloma randomly assigned to either high-dose therapy or conventional therapy". Medicine (Baltimore) ;84:250-60.

7-Hutcherson, D., K. Valla, K.S. Shah, et al. 2014. "Simplified Technique for Administration of High Dose Melphalan." Biology of Blood and Marrow Transplantation 20(2): S291-S292.

8-Attal, M., J. L. Harousseau, A. M. Stoppa, et al. 1996. "A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome." N.Engl.J.Med. 335(2):91-97.