7+3+GO PROTOKOLÜ

Kaynaklar:

1-Lambert J et al. Gemtuzumab ozogamicin for de novo acute myeloid leukemia: final efficacy and safety updates from the open-label, phase III ALFA-0701 trial, Haematologica 2019. 104(1):113-9

2-NICE. TA545 Gemtuzumab ozogamicin for untreated acute myeloid leukaemia. Published 14/11/2018. 

3- Caron PC, Jurcic JG, Scott AM, et al. A phase 1B trial of humanized monoclonal antibody M195 (anti-CD33) in myeloid leukemia: specific targeting without immunogenicity. Blood. 1994;83(7):1760–1768. 

4- Castaigne S, Pautas C, Terre C, et al. Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study. Lancet. 2012; 379(9825):1508–1516. 

5- International System for Human Cytogenetic Nomenclature. Guidelines for cancer cytogenetics. In: Mittelman F, ed. Supplement to an International System for Human Cytogenetic Nomenclature. Basel, Switzerland: Karger; 1991:1–53. 

6- Hills RK, Castaigne S, Appelbaum FR, et al. Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukaemia: a meta-analysis of individual patient data from randomised controlled trials. Lancet Oncol. 2014;15(9):986–996. 

7- Burnett A, Cavenagh J, Russell N, et al. Defining the dose of gemtuzumab ozogamicin in combination with induction chemotherapy in acute myeloid leukemia: a comparison of 3 mg/m² with 6 mg/m² in the NCRI AML17 Trial. Haematologica. 2016;101(6):724–731.